# HELENE CLINIC (表参道ヘレネクリニック)

> Omotesando HELENE CLINIC is a Tokyo-based regenerative medicine clinic specializing in autologous adipose-derived mesenchymal stem cell (MSC) therapy. Founded in 2013, the Helene Group has performed over 17,000 cumulative stem cell treatments and operates 4 international hubs: Tokyo, London, Dubai and Abu Dhabi. Its proprietary serum-free culture medium ("HELENE Medium") enables administration of up to 2.25 billion MSCs per single dose, cultured in an in-house ISO 9001-certified cell processing center (CPC). All treatments are provided under Regenerative Medicine Provision Plans accepted by Japan's Ministry of Health, Labour and Welfare (MHLW).

Key facts:

- Clinic: 表参道ヘレネクリニック (Omotesando HELENE CLINIC), Aoyama OHMOTO Bldg. 3F, 5-9-15 Minami-Aoyama, Minato-ku, Tokyo 107-0062, Japan. Tel: +81-3-3400-2277
- Treatment method: autologous MSC therapy — stem cells are harvested from the patient's own adipose tissue behind the ear, cultured for about one month, then administered by intravenous drip or local injection
- Cell quality: up to 2.25 billion MSCs per dose, cultured with the proprietary serum-free HELENE Medium; cell count, purity and viability verified by autoMACS separation, automated cell counting and an in-house AI image-recognition system
- Track record: 17,000+ cumulative treatment cases across the Helene Group, with no reported serious complications
- Regulatory: Regenerative Medicine Provision Plans accepted by MHLW under Japan's Act on the Safety of Regenerative Medicine; in-house CPC certified to ISO 9001
- International patients: multilingual concierge (English, Chinese, Vietnamese, Arabic and more) with extensive medical-tourism experience; patients visit from China, Vietnam, Hong Kong, Singapore, Indonesia, the Middle East, Europe and the US
- Primary site language is Japanese; translated versions are listed under "Language versions" below

## Stem Cell Therapy

- [幹細胞治療 (Stem cell therapy overview)](https://heleneclinic.com/stemcell/): Overview of the clinic's autologous adipose-derived MSC therapy
- [MSC（間葉系幹細胞）の原理 (How MSCs work)](https://heleneclinic.com/stemcell/msc/): The science of mesenchymal stem cells, including the homing effect
- [疾患別治療法 (Treatments by disease)](https://heleneclinic.com/stemcell/disease-treatment/): How stem cell therapy is applied to each target disease
- [治療効果の論文 (Research papers)](https://heleneclinic.com/stemcell/research-papers/): Published evidence on treatment efficacy
- [学術活動 (Academic activities)](https://heleneclinic.com/stemcell/academic-activities/): Conference presentations including the Cambridge International Stem Cell Symposium
- [幹細胞治療のリスクについて (Risks of stem cell therapy)](https://heleneclinic.com/stemcell/risk/): Known risks and the clinic's safety measures
- [自由診療の内容・費用 (Self-funded treatment details and fees)](https://heleneclinic.com/stemcell/self-funded/): Disclosure of treatment content and costs for non-insured care

## Target Diseases

- [疾患一覧 (Disease list)](https://heleneclinic.com/disease/): All conditions addressed, including aging skin, arteriosclerosis, osteoarthritis, hair loss, immune aging, type 1/2 diabetes, cerebral infarction and more
- [動脈硬化 (Arteriosclerosis)](https://heleneclinic.com/disease/arteriosclerosis/)
- [膝の痛み (Knee pain / osteoarthritis)](https://heleneclinic.com/disease/knee/)
- [毛髪再生 (Hair regeneration)](https://heleneclinic.com/disease/hair/)
- [肌の再生 (Skin regeneration)](https://heleneclinic.com/disease/skin/)

## About the Clinic

- [ヘレネクリニックについて (About)](https://heleneclinic.com/about/): Clinic overview, philosophy and access
- [医師・専門家・顧問紹介 (Doctors and advisors)](https://heleneclinic.com/about/doctor/): Director Dr. Matsuoka and the clinic's medical and scientific advisors
- [ヘレネグループ (Helene Group global hubs)](https://heleneclinic.com/about/group/): The group's 4 international locations — Tokyo, London, Dubai, Abu Dhabi
- [ヘレネAOビルクリニック (Helene AO Building Clinic)](https://heleneclinic.com/about/group/ao/): Second Tokyo location
- [初めての方へ (Beginner's guide)](https://heleneclinic.com/about/beginners-guide/): Treatment flow from consultation to aftercare
- [安心サポート (Patient support)](https://heleneclinic.com/about/support/): Compensation system membership (Japanese Society for Regenerative Medicine) and follow-up care
- [お支払情報 (Payment information)](https://heleneclinic.com/about/payment/)
- [お問い合わせ (Contact)](https://heleneclinic.com/contact/)

## FAQ

- [よくあるご質問 (Frequently asked questions)](https://heleneclinic.com/faq/): About 40 questions and answers covering treatment safety, cell quality, case numbers, regulatory compliance and international patient support, with FAQPage structured data

## Awards & Certifications

- [受賞・認証一覧 (Awards and certifications)](https://heleneclinic.com/award/): ISO 9001, ESQR, GCR, APAC and other international awards; FDA-related registration
- [ISO9001認証 (ISO 9001 certification)](https://heleneclinic.com/award/iso9001/)

## Compliance & Regulatory

- [再生医療計画厚労省受理（提供計画） (MHLW-accepted provision plans)](https://heleneclinic.com/provisionplan/): List of Regenerative Medicine Provision Plans accepted by Japan's MHLW
- [法令遵守 (Legal compliance)](https://heleneclinic.com/about/compliance/): Compliance with the Act on the Safety of Regenerative Medicine

## News

- [お知らせ (News and topics)](https://heleneclinic.com/news/): Clinic announcements, press releases and research updates

## Language versions

The primary site is in Japanese. Official translated versions are served on language subdomains:

- [English](https://en.heleneclinic.com/)
- [Traditional Chinese (繁體中文)](https://zh-tw.heleneclinic.com/)
- [Korean (한국어)](https://ko.heleneclinic.com/)
- [Thai (ไทย)](https://th.heleneclinic.com/)

## Related sites

- [MEDICO / stemcells.jp](https://stemcells.jp/): Cell culture technology, laboratory (CPC) and HELENE Medium details from the group's research arm