Japan-Regulated Regenerative Therapy
For international patients
All treatments are evaluated under Japan’s government-regulated regenerative medicine framework.
- Japan-regulated medical care
- 12+ years of clinical experience
- 17,000+ patients
Online medical pre-assessment available. Treatment provided exclusively in Japan.
Why Patients Choose Japan for Regenerative Therapy
Treatments conducted within Japan's long-established, government-regulated framework for patient safety and protection.
Advanced cell processing centers and quality-controlled laboratories.
Structured treatment journey with pre- and post-care support.
Experienced doctors with a dedicated international patient program and English-speaking coordinators.
Condition-specific regenerative programs including osteoarthritis and type 2 diabetes — eligibility determined by medical review.
Regenerative Medicine Clinic with In-House Cell Processing
HELENE Clinic operates as a specialised regenerative medicine clinic in Tokyo, where medical evaluation, cell processing, and treatment are conducted within a controlled, in-house environment.
Cell processing is performed on-site within our Cell Processing Center, following established quality standards and protocols under Japan’s regulated regenerative medicine framework. All treatment plans are reviewed and approved prior to administration.
- ✓ Autologous stem cell therapies with in-house processing.
- ✓ ISO 9001 certified on-site Cell Processing Center.
- ✓ Treatment plans reviewed under Japan’s regulated medical framework.
- ✓ 12+ years of clinical experience.
- ✓ 17,000+ patients evaluated and treated.
Conditions Evaluated for Regenerative Therapy
Osteoarthritis (MSC Therapy)
Support joint function and mobility by targeting inflammation and cartilage degeneration, evaluated as a non-surgical option.
Type 2 Diabetes (T2DM)
Support metabolic balance and insulin sensitivity through regenerative approaches, subject to structured medical evaluation.
Regenerative Aesthetics & Anti-Aging
Support skin quality and tissue renewal using medical-grade regenerative approaches, evaluated before fillers or surgery.
Disclaimer: Treatment suitability is determined through medical review. Individual responses may vary.
Regenerative Treatment Options Available and Cost Overview
Mesenchymal Stem Cell (MSC) Therapy — Medical Indications
Evaluated for osteoarthritis and metabolic conditions. Treatment approach and scope are determined based on individual medical evaluation.
Treatment approach, dosing, and administration are determined through individual medical evaluation.
Mesenchymal Stem Cell (MSC) Therapy — Regenerative & Longevity Support
Evaluated for patients seeking regenerative and longevity-oriented support. May support systemic balance, tissue health, and recovery through regulated regenerative approaches.
Suitability and treatment planning are confirmed after medical review.
Treatment fees vary depending on medical evaluation, therapeutic indication, and administration method. Final treatment planning and pricing are confirmed only after a doctor’s review under Japan’s regulated medical framework.
Our Regenerative Medicine Specialists
Nana Kobayashi
Clinical Lead
Provides senior clinical leadership in regenerative medicine within Japan’s regulated medical system.
Dr. KOBAYASHI, MD
Takaaki Matsuoka
Representative of HELENE GROUP
Leads regenerative medicine protocols and clinical education. Involved in treatment strategy development and medical oversight.
Dr. MATSUOKA, MBBS, DABRM
Takaaki Itohara
Cardiovascular & Surgical Specialist in HELENE
Provides medical assessment and risk evaluation, particularly for patients with cardiovascular or systemic conditions.
Dr. ITOHARA, MD
All regenerative treatments are evaluated and approved by licensed medical doctors. Treatment suitability is determined through individual medical review.
Your Treatment Journey
Online Medical Review
Submit medical reports for doctor review to assess suitability and treatment indication.
First Visit to Japan
In-person consultation, personalized treatment planning, and tissue collection as required under the approved protocol.
Second Visit
Stem cell culturing requires ~30 days following the initial consultation. After this period, patients return to Japan for therapy administration, according to the approved clinical plan.
Follow-Up Care
Remote follow-up care provided at scheduled intervals as part of the structured treatment plan.
Clinic Location — Tokyo, Japan
HELENE Clinic is located in Tokyo, approximately an 8–9 hour flight, with dedicated support for international patients throughout consultation, treatment, and follow-up.
Certified, Regulated & Trusted
- ✓ ISO 9001–certified quality management system supporting clinical operations and cell processing.
- ✓ Licenses reviewed and approved under Japan's national regulatory framework.
- ✓ Strict hygiene, quality control, and documentation protocols at every stage of care.
- ✓ Dedicated international patient support team for clear communication before, during, and after treatment.
Begin Your Regenerative Therapy Evaluation in Japan
Speak with a medical expert to understand treatment eligibility, medical evaluation, and international travel planning.
Request Medical Review